Inappropriate non-vitamin K antagonist oral anticoagulants prescriptions: be cautious with dose reductions
نویسندگان
چکیده
منابع مشابه
Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation.
For more than 50 years, vitamin K antagonists (VKAs) have been the standard of care for treatment of atrial fibrillation (AF). However, the numerous limitations of VKAs have led to the development of non-VKA oral anticoagulants (NOACs). There are 4 NOACs currently approved for prevention of thromboembolism in patients with nonvalvular AF. This article provides an overview of AF, summarizes basi...
متن کاملNon-Vitamin K Antagonist Oral Anticoagulants: The Clinician's New Challenge.
Millions of US patients are prescribed oral anticoagulants. Traditionally, oral anticoagulation was achieved with vitamin K antagonists (VKAs). In recent years, non-VKA oral anticoagulants (NOACs) have emerged that provide an effective and convenient alternative to VKAs. These agents possess very different pharmacologic properties from what the medical community has grown accustom to with the V...
متن کاملEfficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A Meta-Analysis
BACKGROUND Use of the non-vitamin K antagonist oral anticoagulants (NOACs) is endorsed by current guidelines for stroke prevention in patients with atrial fibrillation (AF). However efficacy and safety of NOACs in patients undergoing catheter ablation (RFCA) of AF has not been well established yet. OBJECTIVES To perform a meta-analysis of all studies comparing NOACs and vitamin K antagonist o...
متن کاملPoint-of-Care Testing of Coagulation in Patients Treated With Non-Vitamin K Antagonist Oral Anticoagulants.
BACKGROUND AND PURPOSE Specific coagulation assays for non-vitamin K antagonist oral anticoagulants (NOAC) are relatively slow and often lack availability. Although specific point-of-care tests (POCT) are currently not available, NOAC are known to affect established coagulation POCT. This study aimed at determining the diagnostic accuracy of the CoaguChek POCT to rule out relevant concentration...
متن کاملNon–Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention in Asian Patients With Nonvalvular Atrial Fibrillation
Stroke prevention with vitamin K antagonists (VKAs) is essential in the management of atrial fibrillation (AF). However, it has been generally perceived that Asian patients are naturally more sensitive to VKAs and have unacceptably higher rates of intracranial hemorrhage (ICH) even when international normalized ratio is ideally maintained. Consequently, VKAs have been largely underused or under...
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ژورنال
عنوان ژورنال: Netherlands Heart Journal
سال: 2019
ISSN: 1568-5888,1876-6250
DOI: 10.1007/s12471-019-1267-9